She was constructed specifically for servicing the scientific bases established in the Chilean Antarctic Territory.

On 4 December 2008, the ship MV Ushuaia grounded at position 64°35.5'S 62°25'W, at the entrance of Wilhelmina Bay, near Cape Anna.

Other vessels to assist were the National Geographic Explorer, Professor Multanovskiy and Polar Star.

Since 2019 the ship was used as a sleeping and working place for UN personal during the UNMHA mission in Yemen, stationed in the harbor of Hodeida.

In May 2020 the Antarctic Dream left Hodeida in regard of the security situation, heading towards Amman (Jordania).