Shortly after the departure, the convoy was spotted by the British submarine HMS Safari, which proceeded to launch torpedoes at the Italian ships, sinking the Loredan with nearly all her crew.

The wreck of the Loredan lies on its left side, with the stern severely damaged, at a depth of between 52 and 67 meters, on the seabed of the Gulf of Cagliari, at 39°08' N and 9°23' E. Today, she is a frequent diving destination.

[1] Rearmed on 12 April, the ship resumed service on line 44 for about a month; then, from May 1940, it operated on the basis of provisions of the Ministry of the Navy, making extraordinary transport journeys on behalf of the government,[2] alternating with moments of rest and partial decommissioning.

[5] At four in the afternoon on 10 April 1943, the Loredan left the port of Cagliari as an escort to a small convoy headed for the archipelago of La Maddalena and formed by the military tanker Isonzo and the old steamship Entella, loaded with 3500 tons of coal.

[7] Shortly after the departure the ships were spotted by the British submarine HMS Safari, which, after having maneuvered to approach and take a position suitable for attack, around 18:20h (in other sources at 18h or 18:25h)[3] launched four torpedoes at the convoy, and then quickly dived underwater and moved away.

[7] The wreck of the Loredan lies on its left side, with the stern severely damaged,[11] at a depth of between 52 and 67 meters, on the seabed of the Gulf of Cagliari, at 39°08' N and 9°23' E. She is a frequent diving destination.