The series stars Lucas Till, George Eads, Tristin Mays, and Justin Hires.

The titles of each episode, with the exception of the pilot, are named after a tool on MacGyver's Swiss Army knife.

Mac, Jack, Sarah, and Nikki attempt to set up a sting to draw out a government mole working for the Organization, while Riley and Bozer visit Murdoc for more information.

A Chinese group uses the chaos as a distraction, aiming to steal a top-secret weapon called "Project 23" from the building.

[24] The eighteenth episode, "Flashlight" featured guest appearances by Hawaii Five-0 actors Daniel Dae Kim, Grace Park, and Taylor Wily as Lieutenant Chin Ho Kelly, Officer Kono Kalakaua, and Kamekona Tupuola, respectively.

[25] The Phoenix Foundation was subsequently mentioned in the Hawaii Five-0 seventh season episode "Puka 'Ana" which aired immediately following "Flashlight".

[31] It was also reported that Gemmill had backed from the series all together, Paul Downs Colaizzo and Brett Mahoney were announced as the new writers.

[32] In addition, Ancken, Michael Clear, Colaizzo, Mahony, as well as original series creator Lee David Zlotoff all signed on as executive producers.

[31] It was revealed on March 21, 2016, that Lucas Till and Joshua Boone had been cast as Angus MacGyver and Gunner, respectively.

[32] Later cast were Addison Timlin and Michelle Krusiec as Mickey and Department of Homeland Security Agent Croix.

[51] Meanwhile, Daniel Dae Kim, Grace Park, and Taylor Wily all appeared in an episode as their respective Hawaii Five-0 characters.

[55] When reviewing both MacGyver and the Lethal Weapon TV adaption Maureen Ryan with Variety said "Lucas Till's performance as the title character misses the mark completely" and that "Both programs seem like broken relics from a time capsule".

[56] Daniel Fienberg from The Hollywood Reporter says "Despite a blockbuster director at the helm, it's a shoddy product made out of the sort of ill-fitting bits and bobs that Angus MacGyver himself might fashion into a bomb".

[57] Following the season finale Matt Webb Mitovich of TVLine stated "I find the five-person cast a bit claustrophobic, and I’m on record as not being a fan of new boss Matty Webber".