It lies on the Stafford to Manchester branch of the West Coast Main Line in the United Kingdom.

Facilities at the station include ticket sales, a kiosk, a waiting room and public toilets.

It is one of the three stations that provide access to the Middlewood Way, which follows the route of the former Macclesfield, Bollington and Marple Railway.

The London and North Western Railway (LNWR) opened the line between Manchester and Macclesfield on 19 June 1849.

The new MB&M station was connected to the rest of the joint line for goods on 3 April 1871 and opened for passengers on 1 July 1873.

[6] Macclesfield is served by Avanti West Coast, CrossCountry and Northern Trains services.