It was formed in the 2003 merger of Macdonald-Cartier High School of Saint-Hubert, Quebec, with Richelieu Valley Regional High School of McMasterville, Quebec.

As of 2024, Heritage Regional High School serves 1761 students.

[2] HRHS offers curricular focus programs in general studies, International Baccalaureate, fine arts, computer applications and networking, sports excellence, and an alternative work-study program.

[3] Macdonald-Cartier High School, an English-language school named in honour of two Fathers of Confederation, Georges-Étienne Cartier and John A. Macdonald, opened in September 1968 in St. Hubert, with space for 3000 students.

[4] The French Mouvement pour l'Intégration Scolaire opened the Richelieu Valley Regional High School in McMasterville in 1969 to accommodate French-language students.