[2][4] After the Kosovo war in 1999, the organisation provided large-scale support to refugees arriving in the country, as well as to the families displaced during the 2001 insurgency in Macedonia.

Macedonian Caritasteams were distributing food and hygiene packages, hot meals and clothing to refugees and migrants at the border with Greece as well as.

[6] In 2017, the organisation established the Mother Teresa Centre in Gevgelija, offering daycare services for children and young people with special needs.

[10] In 2023, it partnered with the National MS Association to deliver groceries, firewood, and therapy to individuals affected by multiple sclerosis.

[11][12] Additionally, it has offered support to victims of local natural disasters, such as storms,[13] and has raised funds for international emergencies, such as the 2019 earthquake in Albania.