Macguire McDuff (born February 28, 2003) is an American swimmer and former USA National Team Member.

Additionally, he reached the final in the men's 100-meter freestyle at the 2023 USA Swimming Championships.

[6] At the 2024 SEC Swimming & Diving Championships, McDuff helped set the American record in the 200-yard medley relay.

[9] Later that year, McDuff competed at the 2024 USA Olympic Swimming Trials in Indianapolis, Indiana.

[10] On September 23, 2024, McDuff, who was at the peak of his career and heading into his senior season at Florida, unexpectedly announced his retirement from competitive swimming.