Satonaka—who admired the works of Osamu Tezuka, Shotaro Ishinomori, Tetsuya Chiba, and Hideko Mizuno—was filled with a desire to "protect manga" and to "contribute to raising its status" in society by becoming an artist herself.

[2] In 1964, during her second year of high school, Satonaka made her professional debut with the one-shot Pia no Shōzō ("Portrait of Pia"), published in Kodansha's Shōjo Friend magazine; for this, she received the inaugural Kodansha New Faces Award.

[4] As of 2019, Satonaka has created nearly 500 manga for both shōjo (young girls) and josei (adult women) in a variety of genres, including romantic comedies, fantasy epics, and historical dramas.

[5][6] Her longest-running manga, Tenjō no Niji ("Celestial Rainbow"), depicts the life of the Japanese Empress Jitō and was serialized for more than 30 years.

[8][9][10] Masami Toku, a scholar and professor of art education at California State University, Chico, described Satonaka as an artist who "consistently protested against a stereotypical male view of women, which often demanded that they remain young and immature, and instead wholeheartedly affirmed women's growth and maturity.