She writes both fiction and non-fiction about topics including sexuality and the role of women throughout history.

[2] Lee has a Master of Fine Arts from Simmons University in writing for children and young adults.

In the promotional period for this book, she began posting on Twitter under the hashtag #BygoneBadassBroads, sharing biographies of notable women beginning with Mary Shelley.

This project grew in popularity, and in 2018, Lee published Bygone Badass Broads: 52 Forgotten Women Who Changed the World.

[2][4] Her second novel, entitled The Gentleman's Guide to Vice and Virtue, was a New York Times Best Seller and earned a Stonewall Book Award for its portrayal of a bisexual young man in 18th-century Europe.