Macrogryphosaurus (meaning "big enigmatic lizard") is a genus of elasmarian dinosaur from the Coniacian age Upper Cretaceous Sierra Barrosa Formation (Neuquén Group) of Argentina in Patagonia.

In May 1999, during field work at Mari Menuco Lake, Argentina (sixty kilometres northwest of Neuquén) conducted by the National University of Comahue, an articulated, nearly complete dinosaur skeleton was discovered and excavated.

[1] The holotype specimen, MUCPv-32, consists of an essentially complete set of vertebra, a number of ribs, four mineralized thoracic plates, both sides of the pectoral girdle, and a sternum.

It was not determined to belong to a Macrogryphosaurus, but noted to be from an animal of similar size and anatomy, and from approximately the same geographic and stratigraphic location, though it lived at a slightly earlier time.

[5][6] M. gondwanicus received a complete osteology in 2020, a study published in Cretaceous Research by Sebastián Rozadilla, Penélope Cruzado-Caballero, Jorge O. Calvo.

[8] Heterodontosauridae Eocursor Thyreophora Lesothosaurus Agilisaurus Hexinlusaurus Yandusaurus Nanosaurus Haya Jeholosaurus Changchunsaurus Orodromeus Koreanosaurus Zephyrosaurus Yueosaurus Thescelosaurus Marginocephalia Parksosaurus Talenkauen Macrogryphosaurus Gasparinisaura Galleonosaurus Leaellynasaura Anabisetia Diluvicursor Hypsilophodon Rhabdodontidae Muttaburrasaurus Tenontosaurus Dryomorpha