[1] In 2007, Zima played the main role of Mia Lewis in the first two seasons of the Showtime comedy-drama Californication alongside David Duchovny, appearing as a guest in series 3 & 4 through to 2011.

[1] In promotion of the fictional book her character wrote, Fucking & Punching, Zima starred in several Californication webisodes featured on YouTube.

[5] Zima has also become known for her work in films such as The Hand That Rocks the Cradle,[6] A Cinderella Story,[6] Dimples,[6] Looking for Sunday,[6] Once in a Very Blue Moon,[6] Legacy[6] and The Collector.

[6] in 2009, Zima joined the cast of Heroes[7] as Gretchen Berg, Claire Bennet's quirky bisexual roommate and tentative love interest.

[12] Zima was nominated three times for a YoungStar Award, in 1995, 1997 and 1999, all for Best Performance by a Young Actress in a Comedy TV Series for The Nanny.