[1] Weinstein is the creation and alter ego of underground filmmaker Richard Bluestein and was described by USA Today as "representative of the type of over-the-top content that would never see the light of day at a mainstream media outlet".

She is the self-professed "Margaret Mead of podcasting" as she is an amateur cultural anthropologist who, in her free time, studies the sordid sexual activities of homosexual men.

Weinstein's most notable lesbian relationship was with Gussie Iscowicz (the alter ego of Bluestein's late partner Juan Montealegre), an elderly hairdresser living in Miami, Florida who suffered from Alzheimer's.

Madge Weinstein and Wanda Wisdom also co-created the online community Qpodder.org, which collects podcasts by gay, lesbian, bisexual and transgender people or characters.

Not long thereafter, on May 2, 2006, his 14-year-old dog Chauncey, a heavy fixture on the show in its early days including a memorable episode where Weinstein angrily cleaned up his feces, also died.

On September 27, 2006, Richard Bluestein announced on Yeast Radio that he was retiring the character Madge and taking over hosting duties himself due to creative concerns.

In early January 2008, with the threat of her expiring PodShow contract, Weinstein relaunched Yeast Radio as a live show, airing on her website from 10:00 CT on Fridays.

[3] Her show serves as an ongoing protest against censorship, the commercialization of mainstream radio and the continued marginalization of gays and lesbians by the growing monoculture.

The show frequently features original compositions from Taylor E. Ross (described as Madge's "cunt doctor"), the mysterious "Mr. Zeeche" and Dave from the Chub Creek's podcast.

Because of her prominence within the community, Madge also regularly features fellow queer podcasters on her show such as Ragan Fox, Wanda Wisdom, Auntie Vera Charles, Lady Raptastic and Rebecca Nay.