KHSAA District 44[2] KHSAA 5A District 7[2] Madison Southern High School is a public high school located in Berea, Kentucky, United States.

It is one of four high schools in Madison County, Kentucky.

Madison Southern has a variety of nicknames amongst the student body and overall, The Commonwealth of Kentucky, having their school nicknames being Mad South, MadiSouth, "The cousin down South (usually for students attending Madison Central)" and Southern.

Madison Southern also has the commonly mistaken alias of "Madison Central", usually at sporting events where the school is judged, like in Cheerleading or Marching Band.

Madison Southern KMEA Marching Band Championships (2) Class A Madison Southern KMEA Marching Band Distinguished Rankings (14) To receive a distinguished trophy from KMEA, The band MUST get a score of 80 or higher at a state-sanctioned competition.