Madonna and Child with Angels or Madonna and Child Surrounded by Angels is an oil-on-panel triptych painting by Quentin Matsys, executed c. 1509, now in the Museum of Fine Arts of Lyon.
The work, which was originally intended for private devotion, seems to echo the art of Jan van Eyck.
The painting shows the Virgin Mary with long hair, standing under an arch with solid columns of onyx and crystal.
Two putti frame the scene in the upper part, one seated on the left capital, the other on the right one.
Visible in the background on the left, next to a small patch of blue sky and a few trees, is a very small section of a church whose elements identify it with the old St. Peter's Church, Leuven.