Largely self-taught, Madosini did not receive formal education but devoted her life to perfecting Xhosa musical traditions under her mother's tutelage.

Though she spent nearly two decades in Langa, Cape Town, Madosini maintained strong ties to her cultural roots in the village of Mkhankatho, Libode district.

Even after her passing, her work continues to serve as a bridge between the rural and the urban, the traditional and the modern, and the local and the global, leaving behind a legacy of haunting beauty and deep cultural resonance.

Although she was paid only R8.00, her music gained popularity, particularly with the song Uthando Luphelile, which became a signature tune for Radio Xhosa (now Umhlobo Wenene FM).

[1] Her breakthrough in the international music scene came in the late 1990s when she collaborated with Professor Dizu Plaatjies and later Robert Trunz of the Meltz2000 label on the album Power to the Women (1998).

[3] Madosini's career spanned decades, during which she collaborated with a wide array of musicians, including South African artists Sibongile Khumalo, Ringo Madlingozi,Thandiswa Mazwai, Msaki, and the younger generation of uhadi instrument players such as Thandeka Mfinyongo, Dumama, Qhawekazi Giyose, Lindokuhle Matina, Mthwakazi, Sky Dladla, Odwa Bongo, just to name a few, as well as international stars such as Patrick Duff, Gilberto Gil, and composer Hans Huyssen, who wrote the oratorio Songs of Madosini performed during a sold-out European tour.

[5] Her collaboration with musicians Hilton Schilder, Jonny Blundell, WhaWha Mosieu and Pedro Espi-Sanchis resulted in the recording of an African/Jazz fusion CD under the name of AmaThongo and various concerts around Africa.

Despite her success, Madosini remained committed to her cultural roots, dividing her time between her home in Langa, Cape Town, and Mkhankatho, where she supported her large extended family.

The fifth movement, "uLoliwe usuka eMtata" ("The train from Umtata"), symbolizes the migration from rural to urban life, mapping South Africa's cultural geography.

"Ndibona uMadiba Sophitsho" ("I see Madiba") is a praise song for Nelson Mandela, expressing gratitude for his role in fostering intercultural dialogue.

This harmonic simplicity contrasts with the rhythmic complexity of her music, characterized by irregular and asymmetrical patterns built around units of duple or triple pulses.