Kazue died when Matsu was still a child, so his mother, to prevent her family from falling into poverty, married Takahata Naokichi, a retainer of the Maeda clan.
Hideyoshi was born from a poor background, and he was friends with Toshiie from an early age; it is said that they both helped Omandokoro with the family's crops and shared the rewards together.
Matsu personally advanced the battlefield and asked for mercy for the Maeda clan, Hideyoshi was thrilled with her words to spare her husband.
The position of wife of a warlord was more political than marital, so Matsu is famous for being extremely skilled in fighting, in domestic and also military affairs.
After days of battle, Hideyoshi's victory was certain, so Katsuie committed seppuku, after killing his wife, Oichi (Nobunaga's sister) and other members of his household, and set it on fire.
When Sassa Narimasa posed a threat to Suemori Castle in 1584, Toshiie hesitated to answer the call and risk his life in battle.
Then Toshiie left the defense of the castle because of Okumura Nagatomi and his wife Katō Tsune to expel the 15,000 soldiers from the coalition of Sassa Narimasa and Tokugawa Ieyasu.
Then Maeda Matsu confronted Toshiie, mocking him, she said a phrase that became famous in history:"How about bringing your gold and silver along by poking through them with your spear?"
Because of Matsu's confrontation, Toshiie appeared in the battle as reinforcements, then Nagatomi and Tsune successfully managed to defend Suemori castle.
After the unification, Hideyoshi and Toshiie clashed in 1595 over the inheritance of Tsuruchiyo, a son born to one of Nobunaga's daughters (Fuyuhime) and the late Gamō Ujisato.
Hideyoshi was preparing the boy to become one of his possible successors and Toshiie disapproved of him from various angles, refusing to attend Osaka castle for three years.
Nene passed the news to Hideyoshi who reflected and finally addressed the retainers' anger for leaving the Gamō clan without a successor.
However, the situation would not be easily controlled, so Ishida Mitsunari under the influence of Hideyoshi's most loyal retainers and Hideyori's mother, Yodo-dono, went to war against Tokugawa Ieyasu.
In 1600, Toshimasa sided with Western army, supported Ishida Mitsunari during the Sekigahara Campaign and had evidently plotted to assassinate Tokugawa Ieyasu beforehand.
Her brother Maeda Toshinaga (Matsu's first son) sided with Eastern army of Tokugawa Ieyasu after Hosokawa Tadaoki convinced him.
Matsu spent 14 years as a prisoner at Edo Castle, the capital of the new shogun, Tokugawa Ieyasu, whom she hated as she watched him, her husband, and Hideyoshi vying for power.
She struggled to maintain a friendly relationship with the members of the Tokugawa family, due to her determination, Ieyasu spared the Maeda clan from being annihilated and offered feuds and high social status to Matsu's children.