[2] Kehres and Maguire suggest that the MgtE proteins are secondary carriers with inwardly directed polarity.

Maruyama et al. showed that MgtE exhibits the channel-like electrophysiological properties, i.e., Mg2+ transport occurs in accordance to the electrochemical potential of Mg2+.

The crystal structures of the MgtE dimer reveal that the Mg2+-sensing cytoplasmic region consists of the N and CBS domains.

The Mg2+-bound state adopts a compact, globular conformation, which is stabilized by the coordination of a number of Mg2+ ions between these domains.

The transport reaction catalyzed by MgtE proteins is: As of this edit, this article uses content from "1.A.26 The Mg2+ Transporter-E (MgtE) Family", which is licensed in a way that permits reuse under the Creative Commons Attribution-ShareAlike 3.0 Unported License, but not under the GFDL.