The station serving as the western terminus of the narrow gauge Clogher Valley Railway opened on 2 May 1887 and was shut on 1 January 1942.

[3] On 17 November 1981 Albert Beacom, a Corporal in the Ulster Defence Regiment, was shot dead by the Provisional Irish Republican Army while working on his farm outside Maguiresbridge.

[4] On 11 February 1986 an off-duty member of the Royal Ulster Constabulary Derek Breen (aged 29) was shot dead by the Provisional Irish Republican Army in the Talk of the Town Bar (now the Coach Inn).

During the same incident John McCabe (aged 25), who was working as a barman there, was caught in the gunfire and died on scene.

Bernadette Collins, who worked as head of race strategy for the Aston Martin Formula One Team from 2020 to 2022, was born and raised in the town.