Born in Blacktown, New South Wales, Murphy played her junior rugby league for the Doonside Roos and attended Hills Sports High School.

[3] On 3 May 2015, Murphy made her Test debut for Australia, scoring a hat-trick in a 22–14 win over New Zealand.

[5] On 24 September 2020, Murphy returned to rugby league, joining the St George Illawarra Dragons NRL Women's Premiership team.

[6] In Round 1 of the 2020 NRLW season, she made her debut for the Dragons, coming off the bench in a 18–4 loss to the Sydney Roosters.

[11][12] She made the Wallaroos squad for a two-test series against the Black Ferns at the Laurie O'Reilly Cup.