Mahmoud Abou-Regaila (Arabic: محمود أبو رجيلة; born 9 September 1941), also known as Abo Regala, is a former Egyptian footballer and former head coach of Zamalek.

He received honours as a player in the 1965 Pan Arab Games and as a manager in the 1999 Egypt Cup.

He won 3 Egyptian Premier League titles with Zamalek and 2 Egypt Cup titles.

With his country, he won the 1965 Pan Arab Games.

As a head coach, Abou-Regaila won with Zamalek the 1983-84 Egyptian Premier League, 1984 African Cup of Champions Clubs and the 1999 Egypt Cup title.