Working his way up the judicial ladder, he was eventually appointed vice-president of the Court of Cassation (Arabic: محكمه النقض)., which represents the final stage of criminal appeal in Egypt.
Makky also demanded the amendment of article 76 of the Egyptian constitution to allow multiple presidential candidates to run for elections.
[9] Makky had a popular position in 2006 when he surprised the judges and the broad masses huddled in front of the High Court after the end of the first session of the disciplinary trial for Makky and ran quickly towards Major General Ismail Shaer, director of Cairo security.
[2] On 22 December 2012, Mekki resigned from his post, stating that "I have realized a while ago that the nature of politics does not suit my professional background as a judge.
After his resignation Makky assumed the role of the chairman of a national dialogue forum to consolidate political forces with the Qandil cabinet.
[12] President Morsi appointed Makky as Egypt's Ambassador to the Vatican City on 17 January 2013.