Mailly-Champagne (French pronunciation: [maji ʃɑ̃paɲ]) is a commune in the Marne department in north-eastern France.

Mailly-Champagne is a small village inserted in Champagne vineyard on the north of the Montagne de Reims, 8 km south of Reims, and on the north of Épernay.

The village's vineyards are located in the Montagne de Reims subregion of Champagne, and are classified as Grand Cru (100%) in the Champagne vineyard classification.

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