The Main Choral Synagogue (Russian: Главная хоральная синагога, romanized: Glavnaya khoral'naya sinagoga) is a former Orthodox[citation needed] Jewish congregation and synagogue, that is located at 70 Baumana Street, in Rostov-on-Don, in the Rostov Oblast of Russia.

Completed in 1868, the building served as a synagogue until 1935; was nationalized and then rebuilt after the October Revolution; and currently operates as a hospital, for the Skin and Venereal Diseases Dispensary.

It was located between the present-day Bauman and Ulyanovsk streets near Voroshilov Avenue.

He noted in his speech that he aims "to equate Jews in terms of social position with the rest of the citizens of the city.

"[3] In 1881 there was built and attached to synagogue a house of worship, which could hold up to 150 people.

The appearance of the synagogue façades was also seriously distorted: the old windows were enlarged, much of the stucco decorations were destroyed.