The Main Guard, originally called the Guardia della Piazza, is a building in Valletta, Malta, located in St George's Square facing the Grandmaster's Palace in the city centre.

[4] Some time later, the trophies were removed, and a relief of the British coat of arms was added above the portico, with the following Latin inscription below it:[1][5] magnæ et invictæ britanniae melitensium amor et europae vox has insulas confirmat a.d. 1814 (meaning The love of the Maltese and the voice of Europe assigned these Islands to great and unconquered Britain.

[6] The design of the portico is attributed either to the Maltese architect Giorgio Pullicino, or to Colonel George Whitmore of the Royal Engineers.

Life in the Main Guard was quite boring, and many soldiers painted or carved regimental badges or other things on the walls of the building.

The Main Guard subsequently became an annex of the Office of the Attorney General until it was eventually transferred to Heritage Malta for restoration.