Main Sequence is a chestnut horse with a narrow white blaze bred in Kentucky by Flaxman Holdings an organisation which deals with the breeding and racing interests of the Niarchos family.

[3] Ikat's dam, Burning Sunset was a half-sister to The Oaks winner Light Shift and a granddaughter of the leading French-trained racemare Northern Trick.

[5] Main Sequence began his second season in a handicap over ten furlongs at Newmarket on 17 April in which he carried 132 pounds and started the 2/1 favourite against seven opponents.

He took the lead inside the final furlong and won by half a length from the filly Ahzeemah (later to win the Lonsdale Cup) although he again showed signs of temperament as he "flashed" his tail under pressure.

[6] The colt was then moved up in class and distance to contest the Group Three Derby Trial over one and a half miles on the Polytrack surface at Lingfield Park.

In a rough race he struggled to obtain a clear run in the closing stages and appeared an unlucky loser, finishing fourth, a length and a half behind the winner Imperial Monarch.

[8] Main Sequence started favourite for the Great Voltigeur Stakes at York Racecourse on 22 August, but failed to quicken in the straight and was beaten a neck by Thought Worthy, with Encke in third and Noble Mission in fourth place.

On his final appearance of the season, the colt started joint second favourite for the St Leger at Doncaster Racecourse, but although making progress in the straight he finished fifth of the nine runners behind Encke and Camelot.

[9] He was dropped in class in June for a race at Pontefract and started favourite, but finished fourth to Brown Panther, beaten thirteen lengths by the winner.

Main Sequence took time to acclimatise to his new base and did not race until July 6, when he contested the Grade I United Nations Stakes over eleven furlongs on turf at Monmouth Park.

Ridden by Rajiv Maragh he started at odds of 8/1 in a nine-runner field headed by the Canadian colt Kaigun and the Tom Albertrani=trained Twilight Eclipse.

In the closing stages, the gelding produced a sustained run to catch Imagining in the final stride and won by a head in a time of 2:24.72 with Twilight Eclipse in third.

"[12] On September 27, Main Sequence attempted to gain his third consecutive Grade I victory in the Joe Hirsch Turf Classic at Belmont Park.

The racecourse stewards held an inquiry into interference caused when Main Sequence hung to the left in the closing stages and bumped the runner-up, but allowed the result to stand.

As usual, Main Sequence was restrained in the early stages as Imagining set a steady pace before Hardest Core took over after half a mile.

[14] On his first appearance in 2015, Main Sequence started the 3/5 favourite for the Grade II Mac Diarmida Handicap over eleven furlongs at Gulfstream Park.