[2] In 1957 it was named after Mayor John T. Alsop Jr., but continues to be known, even on road signs, as the Main Street Bridge.

The Main Street Bridge took three years to be built and had a dedication ceremony on July 17, 1941.

The bridge carries traffic to and from San Marco, Southbank, Downtown Jacksonville and Interstate 95.

In 2014 the Main Street Bridge underwent an $11 million renovation to upgrade metal barriers and patch sidewalks.

Of the eight vehicle crossings in the region, four (Shands, Fuller Warren, Acosta and Main St.) had included movable spans when they initially opened.