The last 3.85 kilometre-long section was owned by the Grand Duchy of Baden State Railway (Großherzoglich Badische Staatseisenbahnen).

All through passenger trains had to push back from the main station to the junction and then reverse to continue their journey.

[2] Passenger traffic on the Main and Tauber Valley Railways is operated by Westfrankenbahn, a subsidiary of Deutsche Bahn.

Due to the cycle tourism in the Main and Tauber Valley, the line is enjoying greater popularity.

Regional-Express services run every two hours as the Main-Tauber-Express from Aschaffenburg to Crailsheim and thus do not require a change at Wertheim.

Since the timetable change in 2017, a train composed of double-deck cars and two class 218 locomotives is also operated on this route.