It heads due east along Presque Isle Road passing some gas stations, markets, Ashland District School, and houses.

SR 163 makes another curve to the northeast where it climbs a hill to the south of Haystack Mountain.

At first, the road (carrying the name Main Street) passes mostly houses, but also a church and the post office.

SR 163 continues east on Parsons Road Connector around the north side of downtown Presque Isle.

Continuing east, it passes to the south of Aroostook Centre Mall and various other stores while it briefly expands to four lanes.

It necks down to two lanes as it crosses over a railroad and ends at Fort Fairfield Road, SR 167.