[1][2] Mains d’Œuvres is situated in a refurbished Valeo car factory, which was used as an employee community and sports center until the company sold the building in 1991.

A pioneer of its time, Mains d'Œuvres spearheaded the widespread phenomenon in Europe during the 1990s, which consisted of turning factories into placed dedicated to new, inventive art forms.

[3] Attributing its outlook to Gilles Deleuze's Difference and Repetition, Mains d’Œuvres describes itself as, "Sensual and intellectual, specialist and non-specialist...an experimental art space open to everyone.

Consecutively in 2006, 2007, and 2008, Mains d'Œuvres hosted The Mal Au Pixel festival of electronic art and subcultures, presenting original experiences based on interactive and participative works, hybrid performances, concerts and other unexpected encounters.

[6] Mains d’Œuvres offers dance residency programs that are open to projects which are singular in their research as well as in their attempt to (re)question or rethink society and the art of choreography.

Mains d'Oeuvres has held several exhibitions showcasing artists such as Wim Delvoye, Thomas Hirschhorn, Sophie Calle, Jon Bernad, Neil Beloufa, Pauline Bastard, Ivan Argote, Dominique Blais, Etienne Jaumet, Herman Dune, and Marie Hendriks.