Unlike Nagai's earlier Cutie Honey, Majokko Tickle is much similar in structure to Toei Animation's previous slate of magical girl series, with a younger demographic than the former.

Tickle uses her powers to solve everyday problems and, of course, to continue playing tricks on people (particularly Chiko's annoying kid sister, Hina).

The duo were tremendously popular at the time of the series's inception, with their song "Southpaw" later being utilized in an episode of the show as Tickle, Chiko, and Hina watch them perform on television.

Masaki Tsuji, longtime friend of Nagai and head writer on his earlier series Devilman, Dororon Enma-kun, and Cutie Honey, contributed scripts to Tickle.

The Italian, French and Spanish dubs also have completely replaced the music and effects track from the original Japanese version.

Additionally due to this situation, Tickle's appearance in the 1999 role-playing video game Majokko Daisakusen: Little Witching Mischiefs (which featured magical girls from Toei Animation TV series from 1966–1981, including Cutie Honey, Megu-chan, Sally, and Akko-chan among others) was not possible.