Make Mine Laughs is a 1949 American musical comedy film directed by Richard Fleischer.

Comedian Gil Lamb hosts the proceedings, finding time to make satirical comments about the opening credits and to perform his "swallowing the harmonica" specialty.

The film clips include two short subjects, Leon Errol's Beware of Redheads and two clips from RKO's Flicker Flashbacks entries (a 1920 fashion show narrated by radio's Ward Wilson and a dramatic playlet narrated by Knox Manning).

Other clips from the vaults are Frances Langford singing "Moonlight Over the Islands" (from The Bamboo Blonde), Anne Shirley and Dennis Day duetting on "If You Happen to Find a Heart" (from Music in Manhattan), comedy bandleader Freddie Fisher (from Seven Days Ashore), dance team Rosario & Antonio (from Pan-Americana), and pianist-bandleader Frankie Carle from an RKO short subject.

The studio avoided any future lawsuits by confining its remaining variety-show features Footlight Varieties and Merry Mirthquakes to new numbers staged especially for the films, and comedy sequences from RKO's backlog of short subjects.