Makedonska Kamenica (Macedonian: Македонска Каменица [maˈkɛdɔnska kaˈmɛnitsa] ⓘ) is a municipality in eastern North Macedonia.

Makedonska Kamenica is also the name of the town where the municipal seat is located.

The municipality is part of Eastern Statistical Region.

The Makedonska Kamenica Municipality has 6,439 inhabitants according to the 2021 North Macedonia census.

Towns: Makedonska Kamenica (Македонска Каменица)