Maki Esther Ortiz Domínguez (born 23 September 1962) is a Mexican politician formerly affiliated with the Ecologist Green Party of Mexico.

She served as mayor of Reynosa from 2016 to 2021, the first woman in the history of the city elected to the position.

She also became the first mayoress to be re-elected for a consecutive second term.

[1] Ortiz Domínguez is seeking election as one of Tamaulipas's senators in the 2024 Senate election, occupying the second place on the Ecologist Green Party of Mexico's two-name formula.

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