Makimachi Misao (巻町 操), in the Media Blasters dub, is a character from the fictional Rurouni Kenshin universe created by Nobuhiro Watsuki.

She leaves her home to find her missing leader Shinomori Aoshi, but instead she encounters with Himura Kenshin during her journey to Kyoto alone.

To prevent additional complications in the storyline, Watsuki wanted Misao as a character who would not develop romantic feelings for Kenshin.

According to Watsuki the setup of the physical design occurred quickly as he "fussed" with an Oniwabanshū ninja outfit "a bit."

She arrives too late to stop the fight and finds Okina barely alive; Aoshi declares he never wishes to see Misao again.

She was also given a letter written by Okina in case he was to die, telling her that she should forget about Aoshi and Oniwabanshu so she can lead a normal life.

[7] Misao becomes close friends with Kenshin, Kaoru, and Yahiko, helping them fight the agents of Shishio Makoto.

She was overwhelmed with this knowledge and cannot stop her own tears, especially because before Kenshin made his statement, Okina had asked him to kill Aoshi.

During the fight with members of the Ten Swords outside Aoi-Ya, Misao is knocked unconscious after fully receiving a hit from Honjō Kamatari's weapon.

She also knocks Kamatari out when he attempts to kill himself to atone for his defeat; she says she cannot truly understand the feelings of a homosexual man but was touched by his loyalty to Shishio.

After all of the Ten Swords present are defeated, they are saved by Hiko Seijūrō and wait for Kenshin, Sanosuke, Saitō, and Aoshi to return.

Misao is sorely disappointed when her new friends decide to return to Tokyo, though Kenshin attempts to cheer her up by assigning her to get Aoshi to smile.

Sagara Sanosuke attempts to reach Kenshin, but his friend is completely lost in his grief and Sano wanders away from Tokyo in despair.

They swear to find Enishi, make him read Tomoe's diary, and beg for forgiveness at Kaoru's grave.

Guided by Aoshi, Misao sets off the bombs in the water surrounding the island, allowing the group to land safely.

Nevertheless, the writer found that Misao's journey to find Shinomori might give her a grim fate as result of what happened to her friends.

[15] Decider praised the focus on Misao and Saito as the play a major role in Rurouni Kenshin: The Final.