[citation needed] In 1988, she moved to Montevideo to study medicine[2] but also joined the acting troupe[2] Antimurga BCG, which was directed by Jorge Esmoris.

[citation needed] Muyala's music career took off in 1991 when she won first prize at the First National Tango Contest of Uruguay, which involved 350 participants from all over the country.

[citation needed] In 1994 she was invited by singer-songwriter Estela Magnone in the group Seda in a concert for her disc Prismatic Vals at the Vaz Ferreira theater.

[7] In December 2008, she was accompanied by the Philharmonic Orchestra of Montevideo for a show called Malena Muyala + La Filarmonica at the steps of the Hotel del Prado to celebrate the tenth anniversary of her first album.

[8] She recorded her fourth CD live and her first DVD called Malena Muyala en el Solís at the Solis Theatre; it was released in 2009.

[jargon][citation needed] In 2011, she performed for Uruguay's bicentennials for events concerning Jose Artigas and the Oriental Revolution at Mercedes, Las Piedras and Montevideo.

[11] She also recorded alongside other major artists a song for the Fundación Celeste, a nonprofit organization put together by the Uruguay national team to promote sports.