It was released on 11 June 2020 through Universal Music Italy, as the lead single from the group greatest hits album Don't Worry (Best of 2005-2020).

The song was firstly written by Federica Abbate, Alfredo "Cheope" Rapetti and Rocco Pagliarulo, and then produced and rewritten by Boomdabash.

[3][4] "Mambo salentino" is the second collaboration between Amoroso and Boomdabash after "A tre passi da te" (2015);[5][6] the group explained the decision to collaborare with the singer:[7]"We are very excited to return to duet with Alessandra an extremely special person for us, not only a friend but a very talented artist with a rare sensitivity.

In fact, our first collaboration dates back to 2015 in "A tre passi da te" and already then we had established a great feeling.

With Salento in our hearts we wanted to work on this new single, which is rooted in the great love we both have for our homeland.