[9] Entertainment Weekly wrote that, "like Eddie Vedder, Varnaline songwriter Anders Parker seems to idolize Neil Young for his twangy introspection; unlike Pearl Jam, he doesn’t weigh down his melancholy with exhibitionistic melodrama.

"[15] The Los Angeles Times opined that the songs oscillate "between very inward folk-pop salted with noisy guitars, and good, muscular, country-tinged expressions of wistfulness, a la Wilco and Son Volt.

"[13] The Chicago Reader determined that, "amid the album's relatively lo-fi hiss, layers of guitar—both clean and distorted—and cheap chord-organ tones, Parker's earnest vocals consistently cut through, exuding a genuine ache typically lacking in such at-home affairs.

"[6] The Record deemed it "a raw, unpretentious project," writing that "Parker's voice is not strong, and is at times tough on the ears as it cracks and strains, but he wrests a great deal of emotion and feeling from it.

"[17] AllMusic wrote: "Kind of like a lo-fi indie version of Bruce Springsteen's Nebraska, Man of Sin is a compelling but occasionally harsh album of real staying power.