Manasota Key is a census-designated place (CDP) consisting mainly of the community of Englewood Beach in Charlotte County, Florida, United States.

"Manasota Key" refers to an 11-mile-long (18 km) peninsula (transformed into a barrier island by the Gulf Intracoastal Waterway) that continues north into Sarasota County.

The key continues north as Caspersen Beach, extending as far as the Venice city limits.

The Manasota Key CDP is located in the northwestern corner of Charlotte County at 26°56′N 82°22′W / 26.933°N 82.367°W / 26.933; -82.367.

Stump Pass is a channel that connects Lemon Bay to the Gulf of Mexico and separates Manasota Key from Don Pedro Island to the south.

Grove City is located directly to the east across Lemon Bay from the south end of Manasota Key.