Manchester houses PBF Battalion 1 & 37 Engine, and is covered by PBP Zone 1 and the Bureau of EMS Medic 4.

The neighborhood includes the Manchester Historic District, which protects, to some degree, 609 buildings over a 51.6-acre (20.9 ha) area.

Manchester began as a village along the shore of the river, providing supplies and services to the surrounding farms.

Manchester was rated as one of the top 10 neighborhoods for "being close to everything" because it's walkable and has easy access to public transportation and major roadways.

According to a report created by the University Center for Social and Urban Research, 46.3% of houses were families while 55.7% were nonfamily households.