Mandeni (also Mandini) is a town in iLembe District Municipality in the KwaZulu-Natal province of South Africa.

These sections are Bhidla, Sikhalambazo, Thokoza, Dark City, Red Hill, Island (sometimes referred to as Ireland), Chappies and White City.

There is also a suburb which accommodated only the Whites during the apartheid era known as eKwatasi.

The town has many factories and attracts workers from near and afar.

The biggest employer is Sappi, the largest paper manufacturer in South Africa.