[12] In 2001, Gonzalez made her debut on Broadway in the role of Princess Amneris in the Tim Rice/Elton John musical Aida as the standby for Idina Menzel.

Gonzalez created the role of Nina in the show's Off-Broadway production and received a Drama Desk Award for her portrayal.

In September 2016, Gonzalez joined the Broadway cast of Hamilton as Angelica Schuyler Church, replacing Renée Elise Goldsberry.

The production, being part of their Broadway Center Stage series, ran a limited run roughly a week long.

In October 2024, she'll begin performances as Nicole Scherzinger's alternate in the Broadway revival and transfer of Jamie Lloyd's production of Sunset Boulevard at the St. James Theatre.

In 2016, Gonzalez starred in the ABC thriller Quantico playing the recurring role of Agent Susan Coombs.

[19] In 2021, Gonzalez had a guest appearance in season 1, episode 6 of the Hulu original series Only Murders in the Building, playing the character Mabel Mora's mother, Silvia.

Gonzalez can be heard on the original Broadway cast recording of In the Heights and in the Disney animated film Mulan II as the singing voice of Su.

Many of her In the Heights friends visited onstage, such as Karen Olivo, Janet Dacal, Priscilla Lopez and Lin-Manuel Miranda.