Provincial Road 346 (PR 346) is a mostly gravel 50.5-kilometre-long (31.4 mi) north–south highway in the Westman Region of Manitoba, Canada.

PR 346 begins in the Municipality of Killarney-Turtle Mountain at an intersection with PTH 3 (Boundary Commission Trail) just south of Ninga.

It heads north as a paved two-lane highway for 5 kilometres (3.1 mi) to enter the hamlet at an intersection with PR 443.

Entering the Rural Municipality of Prairie Lakes, PR 346 goes through a switchback before having a junction with PTH 23 and traveling through Margaret, where it has a brief paved section.

Climbing back out of the valley, though much straighter this time, it enters the Municipality of Oakland-Wawanesa and comes to an end shortly thereafter at a junction with PTH 2 (Red Coat Trail) just on the outskirts of Nesbitt.