Provincial Road 341 (PR 341) is a 33.9-kilometre-long (21.1 mi) east–west highway in the Westman Region of Manitoba.

Running along the northern fringes of Turtle Mountain, it connects the International Peace Garden with the hamlet of Lena, via the nearly abandoned and historic village of Wakopa.

PR 341 begins between the International Peace Garden and the town of Boissevain at a junction with PTH 10 (John Bracken Highway) in the Municipality of Boissevain-Morton.

The highway makes a sharp right turn at an intersection with Road 106W (PR 346 prior to 1992) before heading south past Wakopa and the Mayfair Hutterite Colony.

Curving back eastward, PR 341 passes through rural farmland for several kilometres before entering the hamlet of Lena, coming to an end at an intersection with PTH 18.