He appeared in one game with the first team in the 2005–06 season, against Valencia CF in a 0–0 home draw,[2] as they went on to rank last in La Liga.
However, the club's severe financial crisis led to him becoming first choice after the departure of Marco Storari;[3] in eight matches, he conceded 18 goals.
[8] After their relegation[9] he moved abroad for the first time in his career, joining Cypriot First Division's AEP Paphos FC.
Reina switched teams and countries again on 30 January 2013, signing with Super League Greece club Atromitos F.C.
On 2 July 2013, Reina returned to his country and penned a contract with Segunda División B side Gimnàstic de Tarragona.