Manouselis began his career at the very early age of 20 and has been coaching professionally ever since, working for clubs and, since 2004, the Greek National Basketball Team (NBT).
[citation needed][1] He has won the silver medal at the Men U21 2005 World Championship (Argentina)[2] and the bronze medal at the Men U16 2013 European Championship[3] (Kyiv, Ukraine) as head coach of the respective Greek NBTs.
[citation needed] Manos served as the Assistant Coach of Olympiakos BC,[4] where he was responsible for planning and running daily training sessions and headed the scouting team.
[5] During his tenure, Olympiakos reached the Euroleague Final once and won the 2010 Greek Cup.
[6] During his career he has held head coach positions for a number of teams in both the men's and women's professional leagues in Greece, including Panellinios (1999–2005)[4] which he guided back to Greek Division A1 from Division C and Sporting B.C.