Don Manuel Bermúdez de Castro y Díez (11 June 1811, in Jerez de la Frontera, Spain – 11 March 1870, in Madrid, Spain) was a Spanish economist and politician who served as Minister of Spain between 1865 and 1866, in a unionist cabinet headed by Leopoldo O'Donnell, 1st Duke of Tetuan.
Manuel was the first son of José Bermúdez de Castro y Blasco and María de los Dolores Díez e Imbrechst.
He married in Madrid, on 21 July 1860, María de la Encarnación O'Lawlor y Caballero, daughter of the Irishman Joseph O'Lawlor and Dionisia Caballero y Crooke.
They had a single son: This article about a Spanish politician is a stub.
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