After the resignation of Governor Federico Martínez de Hoz, who intended not to commit electoral fraud again, the National Democratic Party appointed him as its candidate for Governor of the Province of Buenos Aires, a position he achieved thanks to the widespread application of fraud and use of provincial funds for proselytizing acts; he mobilized large numbers of supporters by means of special trains, initiating a particular form of mass democracy.

Fresco's ministers were notable figures, such as the agricultural engineer José María Bustillo, his Minister of Public Works, who was accompanied by the activity of his brother, the architect Alejandro Bustillo; this left its mark on the architecture of the San Carlos de Bariloche region and also on the architecture of Buenos Aires public work, as in the case of the Casino and the Provincial Hotel of Mar del Plata, designed for the growth of the city as a new mass spa after the paving of route 2.

Other renowned ministers were Roberto Noble, who later founded the Clarín newspaper, and Cesar Ameghino, who later became the Ministry of Foreign Affairs and Worship of the governments of the 1943 Argentine coup d'état.

But at the same time, in different speeches, he praised the totalitarian regimes of the German National Socialist Adolf Hitler and the Italian fascist Benito Mussolini, whose busts adorned his office.

In line with this idea, he promoted the construction of cheap housing for the workers, which only remained in preliminary plans, and tried to force the businessmen to pay better wages and a family salary.