Manuel Villanueva Lopez (June 9, 1875 - January 14, 1947) was a Filipino lawyer and politician.

Manuel Lopez was born on June 9, 1875, in Molo, now a district of Iloilo City.

[1] During the Philippine Revolution, he was appointed as the military commander of revolutionary forces in Victorias, Negros Occidental in 1898, and following the Spanish defeat, was promoted by the revolutionary government to become prosecutor and registrar, a role which he continued during the Negros Republic.

[1] From 1906 to 1907, Lopez served as governor of Negros Occidental, during which he helped suppress the revolutionary leader Papa Isio.

Because he received fewer votes than Espiridión Guanco in the district, he won a three-year term and served until 1919.