He played in the minor leagues with Saronno, Brescello, Legnago Salus, Montevarchi, Sangiovannese, Grosseto, Pavia, Lucchese, Alessandria and Olbia.
The following year he played 18 games with the Campanians and in January 2012 moved to Ascoli,[1] where he collected 18 more appearances in the second league, scoring a goal.
After retiring following a season at Cosenza, Scalise stayed under contract with the Calabrian side as a youth coach.
On 1 June 2022, Serie C club Piacenza announced to have hired Scalise as their new head coach on a two-year deal, effective from the start of the 2022–23 season.
[7] On 2 October 2022, he was sacked after a dismal start in the club's campaign, leaving Piacenza at the bottom of the league table.