Manuel Trucco Franzani (March 18, 1875 – October 25, 1954) was a Chilean politician and provisional vice president of Chile in 1931.

Between 1891 and 1902, while still a student at the university, he started to work at the Liceo de Cauquenes to complement his income, first as the secretary to the principal and then as a teacher of mathematics.

After the resignation of president Carlos Ibáñez del Campo in 1931, his successor, vice-President Juan Esteban Montero named Trucco as Minister of the Interior on August 7, 1931.

Since Montero was constitutionally banned from standing as a candidate while still in office, as a way out of the political impasse, and in order to qualify, he resigned his vice-presidency effective on August 20, 1931.

He remained as vice president until November 15, when Juan Esteban Montero resumed power after sweeping the election.